A centuries-old vampire cursed with a conscience, Angel (David Boreanaz) has left the small California town of Sunnydale and the only woman he ever loved to take up residence in the City of Angels. Between the pervasive evil and countless temptations lurking beneath the city’s glittering facade, Los Angeles proves to be the ideal address for a fallen vampire looking to save a few lost souls, and in turn, perhaps redeem his own by restoring hope to those locked in a losing battle with their own demons.
Angel’s solitary existence is disrupted when he crosses paths with another Sunnydale escapee, Cordelia Chase (Charisma Carpenter), who has come to Los Angeles with high hopes of living the glamorous Hollywood dream. A struggling actress who isn’t afraid of anything except someone not recognizing her as the talented, soon-to-be-star that she is, Cordelia finds L.A. and the path to stardom to be rockier than she anticipated. The two discover that they need each other: she for a protective hand in a dangerous city; he for someone with a little moxie to keep him afloat.
They are joined by Doyle (Glenn Quinn), a disreputable spiritual mentor who has been sent by the "Powers That Be," a mysterious and powerful force trying to make things right. A half-human, half-something-else-altogether whose charge is to keep a balance between good and evil, he will guide Angel on his path to redemption, although he would generally rather be at the racetrack.
Doyle’s visions provide very little information beyond a name or face, so it is up to Angel to reach out to people and become involved in their lives to learn how, why, and from whom they need saving. No longer can he simply hide in the shadows; Angel needs to connect with people and let them into his heart to show that there’s hope in the world... and hope for him.